Compact organ-on-a-chip platform

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Micronit has partnered with Fluigent to design a compact platform for any organ-specific experiment.

The organ-on-a-chip platform is an easy setup and enables customisable and dynamic microfluidic flow conditions for tissue culturing, leading to a controlled environment. This opens up great opportunities for next-generation experiments of mimicking human organ functionality, microphysiology and morphology in vitro. Flow interfaces can be liquid-liquid or even gas-liquid for skin or lung tissues growth.

This already widely adapted technology requires fast innovation to let researchers of all disciplines excel in their field. A co-development of Micronit and Fluigent has resulted in a 4-dock OOC system with a pump and flow-rate control integrated that can be operated from a desk but also perfectly integrates in an incubator.

One complete system is modular and scaleable upto 16 flow cells and is a great tool for the lifescience or pharmaceutical researcher.

  • Robust technology
  • Compact system
  • Stable flow-rate and pressure
  • Physiological conditions mimicking
  • Time saving & increased cell growth
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Benefits and Features

 

  • Scalable: the setup is scalable and modular based
  • Compact: one set-up can handle up to 16 chips in parallel in classic size incubators
  • Versatile chip: 2 resealable slides with cell culture membrane
  • Plug and Play: Ability to control gas or liquids with various flow profiles

Organ-on-a-chip technology

  • Organ-on-a-Chip Fluigent technology
  • Very fast response times
  • Excellent stability for long-term experiments
  • Liquid and/or gas interface
  • Robustness and high repeatability


Specifications

  • From 75nL/min to 5mL/min
  • 1 MFCS™-EX, 16 15mL Fluiwells, 8 possible FLOW UNITS, tubing
  • 4 Resealable chips, 4 soft membrane, 1 chip holder
  • Dimensions of 1 platform: 45 x 45 x 28 cm3
  • Weight: 5kg
  • Power Supply: 24V


Possible organ-on-a-chip applications:

Neural or cardio-vascular networks-on-a-chip
Gut-on-a-chip
Liver-on-a-chip
Skin-on-a-chip
Lung-on-a-chip
Mesenchymal stem cells (MSC) or bone marrow-on-a-chip
ESC or iPSC-derived stem cells (ESC/iPSC)-on-a-chip