Main goal of the project
To gain insight into immune-metabolic causes of depression as a comorbidity of cardiovascular disease.
Depression is a common and serious comorbidity of cardiovascular disease (CVD), affecting one in three patients. There is a great need for more insight into the causative mechanisms of CVD-depression comorbidity in order to improve the prevention, diagnosis, monitoring, and treatment of these conditions. TO_AITION addresses the hypothesis that immune-metabolic dysregulation, occurring as a result of genetic, lifestyle, and environmental risk factors drives low-grade systemic inflammation leading to the development of CVD-depression comorbidity.
This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement number 848146.