Materials for Lab on a Chip

Using the best of all worlds…

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Micronit’s approaches the material choice for lab on a chip products starting from the product requirements. From proof of concept to volume manufacturing the whole product development process is focused on manufacturability. Lab on a chip product development can be done in a very similar way as any other product development, selecting the right choice of material for a certain product requirement. For instance for deep UV and high temperature requirements Fused Silica is a great candidate. If one does not require optical transparency but only high thermal conductivity silicon or metal could the material of choice. For low cost high volume disposable with most likely polymer or glass is the material to consider.

The right choice for your product

Micronit’s choice of materials for the product depends on what is the most optimal mix of materials and technologies to fulfill the requirements of the product for the business cases of our clients.

If there is a certain requirement for parts that are made out of materials that cannot be made internally Micronit will take the responsibility of sourcing the parts and integrate it into the product in our cleanroom manufacturing facility.

Micronit combines materials on substrate level or assembles parts made out of different materials into a functional product or cartridge.

Micronit uses all kinds of materials of which mostly used are polymers, glass and silicon. Besides these materials all kinds of surface modifications are present to create the right surface functionalization.

Tailored to your needs

Glass is a good choice if the application needs excellent optical properties combined with chemical inertness and mechanical stability combined with excellent flatness. Most applications that use optical detection benefit from glass as a substrate material. Combining glass with polymers with for instance SideConnect technology allows a cost effective product using the best of the polymer and glass world.

Polymers are a great choice and are often combined with glass. Polymers are great for applications that do not need glass for critical components, polymers are used for low cost disposables. The choice of the right polymer material is critical and depends heavily on the application. The combination of rigid polymer or glass structures with elastomeric membranes allows the integration of valves and pumps.

Silicon microfluidics is used for fast prototyping of high aspect ratio structures and also for the fabrication of masters or moulds for polymer fabrication. Tradition CMOS technology is more and more used for the manufacturing of CMOS base biosensor. The use of silicon base CMOS sensor in microfluidics devices allows the integration of very sophisticated sensors into a fluidic network made out of for instance glass or polymers. Again using the best of all worlds.

Glass materials we use for lab on a chip and microfluidic applications are for instance:

  • Borofloat 33
  • D263
  • Mempax
  • Fused Silica ( Quartz glass)
  • B270
  • AF45
  • AF32
  • other

Silicon materials we use are for instance wafers of 100mm, 150mm or 200mm diameter:

  • <100> silicon wafers
  • <110> silicon wafers
  • <111> silicon wafers
  • Silicon CMOS chip integration
  • Silicon Solar substrates

Polymer materials

  • COC
  • COP
  • Poly Carbonate
  • Polymer membrane materials
  • PDMS
  • Thick film Resists
  • Spin on coatings
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