Microfluidics in Chemistry
In chemistry, micro reaction technology results in a brand new approach if it
comes to chemistry development. Developing new chemicals can be done much
faster, cheaper and safer by miniaturising the reactions.
More concrete, micro reaction technology leads to the following advantages:
- High yield and selectivity
The high yield leads to
reduction of needed chemicals. The high selectivity leads to a reduction of
difficult and costly purification steps.
- High surface to volume ratio
This creates excellent
mass- and heat transfer possibilities. When using a heater or cooler in the
reactor, almost no temperature gradients in the reactor exists. Highly
endothermic or exothermic reactions can be carried out at almost isotherm
conditions.
- Inherently safe processing
Due to the very small
hold-up of fluids in a chip during any part of the process, the processing is
very safe, even when working with dangerous (explosive, corrosive) chemicals.
Therefore, uncommon reaction conditions are possible. The microfluidic devices
Micronit develops can handle pressures up to 100 bar or more, and temperatures
of several hundred degrees centigrade (depending on glass specifications).
- Optical inspection/analysis
When using glass as a micro
reactor construction material, optical inspection of the process is one of the
obvious advantages. And when using specific glass types, even online infrared or
UV spectroscopy is possible.
- Two phase flow in one channel
The use of a microfluidic
chip for chemical reactions enables a two phase flow in one channel.
- Optimal mixing conditions
Multi-layer microreactors can
function as mixer, resulting in very short mixing times, reaching ideally mixed
conditions within very short periods.
Scaling up
Microfluidic chips are
typically used in a modular system. When scaling up a chemical process, no
larger reactor needs to be designed, just more micro reactors are being placed
parallel to each other. Advantages of this modular system are:
- Maintenance is quite easy and cost efficient. No total reactor downtime is
necessary. The defect module is just taken out of the system and repaired.
- Bulk process conditions are the same as "prototype" conditions
- Scaling up is easy and time and cost efficient
The Micronit solution
Micronit offers
a microfluidic solution to the chemical industry. We develop customized,
functionalized glass microreactors with the necessary connection tools. We
functionalize the microreactor, by modifying
the surface and integrating
other materials and electrodes.